Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 2 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 3 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 4 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 5 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 6 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 7 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 8 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 9 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 10 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 11 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 12 of 13

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity — Image 13 of 13

3D model · NIH 3D

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Platform: NIH 3D
Price: Free
License: CC0; Public domain: print, modify and sell, no attribution required.
Formats: GLBSTLWRLX3D

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Author:tj_eyes

Published 2017-03-22

Description

PDB Classifiation: HYDROLASE

Tags

hydrolase signaling small g-protein escherichia coli scalepack phaser hkl-2000 phenix (phenix.refine: 1.6.4_486)bos

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